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You can refuse to take a drug test, however, your employer may have the right to terminate you or refuse to hire you.
An employer may not fire an employee the first time he or she tests positive, but may do so if he or she tests positive more than once. Employers must offer employees who test positive six months of rehabilitation. Employees can be fired if they refuse rehabilitation.
Have you been discriminated against by a potential or current employer -- as a job applicant or current employee? To best protect your legal rights you should discuss your situation with an employment lawyer. Meet with a local employment for employees attorney sooner rather than later to protect your rights.